The Royals are now at the Jubilee House for a brief ceremony with President Addo Dankwa Akufo-Addo.
Early on when he arrived at the Jubilee House, Prince Charles, who was in his cream suit over a white shorts in a gold tie, inspected a full guard of honour mounted by a detachment of the Ghana Army, and took the national salutes of both countries.
The visit which is aimed at strengthening ties between Ghana and the United Kingdom will see the Prince holding discussions with high level government officials.
Prince Charles and his wife Camilla, the Duchess of Cornwall, are taking a page from sons William and Harry and their wives by posing in a series of intimate photos for Vanity Fair to complement the magazine's candid interview with the heir apparent.
"The UK and Ghana's shared history and common values form the basis of our enduring friendship".
After the initial welcome ceremony, the President led Prince Charles to inspect a photo exhibition of the Prince during his first visit to Ghana in 1977.
On Saturday, November 3, the British Royal will call on the Asantehene Otumfour Osei Tutu II at the Manhyia palace.
The British High Commissioner is expected to host Prince Charles to Royal dinner to mark his 70th birthday.
They will also make a trip to the Christianborg Castle which was previously owned by the British.
Britain's Prince Charles, Prince of Wales (R) is welcomed by Gambia's President Adama Barrow (L), upon his arrival at the airport in Banjul, for an official visit. Husband Prince Charles looked dapper, too, choosing a navy double-breasted suit and a pretty floral buttonhole for his arrival.
He will also meet with key players in Ghana's cocoa industry where he will discuss innovative ways to sustain one of the country's most profitable resources.