After his administration pulled the United States out of the Iran nuclear deal negotiated by the Obama administration and several other countries, Trump added: "Additional sanctions will resume November 5 and more will follow". He suggested Washington may eventually decide to come back to the deal.
In a statement after a meeting of Britain, China, France, Germany, Russia and Iran on Monday - the countries still in the deal, the group said they were determined to develop payment mechanisms to continue trade with Iran despite skepticism by many diplomats that this will be possible. "As a matter of fact, America is isolated".
Trump was forced to pause and, to his credit, recovered by saying: "Didn't expect that reaction but that's OK". "The Americans are alone and isolated, and faced with many challenges from its own presence and security".
"If you cross us, our allies, or our partners; if you harm our citizens; if you continue to lie, cheat, and deceive, yes, there will indeed be HELL to PAY", he said.
Without naming countries, the United States president noted that "some nations are already violating UN sanctions" including illegal ship-to-ship transfers of oil and said compliance was "very important".
Nikki Haley, the USA ambassador to the United Nations, said Wednesday morning that the laughter was because people found Trump's response to be so "honest" and that the General Assembly attendees "love to be with him".
The comments came hours after Mr Trump chaired his first UN Security Council meeting in which he criticised Tehran for exporting "violence, terror and turmoil".
Trump announced new USA sanctions on Maduro and his inner circle.
Before Donald Trump took the oath of office, he frequently claimed other countries were laughing at the United States, as a effect of the poor leadership he perceived it to have. "The world is watching". Secretary of State Mike Pompeo's department this week announced publication of a book portraying the Islamic Republic of Iran as an "outlaw regime".
"The regime used new funds from the deal to support terrorism, build nuclear-capable missiles, and foment chaos", Trump said.
"The economic war that the United States has initiated under the rubric of new sanctions, not only targets the Iranian people, but also entails harmful repercussions for the people of other countries, and that war has caused a disruption in the state of global trade", Mr Rouhani said.
"Well, the language wasn't really new", Rouhani said in response to a question about the State Department portraying Iran as an "outlaw regime". "I am sure he is an absolutely lovely man!"
The United States should "stop bullying, and keep the promises it signed on to", he added. "But you should ask him who made such requests".
That attack on Iran has been claimed by Arab separatists and Isis, and Iranian officials themselves have blamed the United States and Gulf countries for the attack.
Macron said that should be "part of an worldwide strategy in order to reduce the dangers for the region and also attain the goal that we all want - namely that Iran does not ever attain a nuclear weapon". "America must think again about her presence in the region". "We do not wish to increase tensions - none of the above".
President Trump addresses the 73rd session of the General Assembly at the United Nations in NY on September 25, 2018.