Walid al-Moualem also said the United States must withdraw from the Tanf base in the southeast. Al-Moallem said Israel is making false claims to try to pressure Iran, its archrival.
The talks also solidified an agreement between Israel and Russian Federation to ensure Iranian and allied forces vacated the southwest region of Syria adjacent to the Israeli border, according to the report. This week, the Russian foreign minister, Sergei Lavrov, said all foreign forces - a reference to Iran and its allied militias - should immediately leave the Daraa province, which borders Israel.
Scores of Iranian soldiers have been killed in battles with insurgents in Syria, including a number of officers.
An element of the Israeli strategy has also been to back up the diplomacy with force in Syria.
Iranian forces and those of its proxy, Hezbollah, are preparing to leave southern Syria, the Syrian Observatory for Human Rights reported.
Both the SDF and Russian-backed Syrian troops are engaged in separate operations against IS in east Syria, creating a highly volatile situation, where de-confliction mechanisms have already been tested several times. However, neither Jerusalem, nor Moscow, publicly acknowledged any agreement between the sides regarding Iran's military presence in Syria.
Iran's advisory help will continue as long as the Syrian government requests it, Shamkhani stressed.
Pentagon spokeswoman Dana White later stated that United States is in Syria only to fight ISIS.
"Any interested party in Syria should understand that attacking USA forces or our coalition partners will be a bad policy", Joint Staff Director Lt. Gen. Kenneth McKenzie told reporters Thursday.
On Friday, Russia's ambassador to the U.N. Vasily Nebenzia said he heard from the news that an agreement was reached on "certain disengagement in the southwest of Syria and, I think, my understanding is that an agreement has been reached".
US President Donald Trump has expressed his plans to pull the US military out of war-torn Syria but officials have persuaded him to allow them to remain until Islamic State fighters are vanquished along the Syria-Iraq border.
The U.S. State Department also said that while Washington is not seeking conflict with Syria, it would use "necessary and proportionate force" to defend U.S. and partner forces, which have teamed up to fight Islamic State militants in the region.
US forces are based in a southern desert pocket further east at Tanf, a strategic highway border crossing with Iraq.
"The U.S. presence in Syria is illegitimate and they should withdraw from al-Tanf and any other area in Syria", he noted.
That would be along Israel and Jordan's borders with Syria.
A senior Israeli official denied Saturday reports that Israel and Russian Federation have reached a deal to see Iranian forces pulled out of southern Syria, Haaretz reports.