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On Tuesday, Ali Akbar Velayati, a top adviser to Iran's Supreme Leader Ali Khamenei, directly threatened Israel saying that the "crime" it committed in striking the airbase "will not remain without response".

Israel is faced worldwide blowback Tuesday over the bombardment of Syria's largest air base, a center for the Iranian military effort to support Syrian President Bashar Assad.

"We will stand by Syria's government against any foreign aggression".

"At least 14 fighters were killed in the strike on the T-4 airport, among them Iranian forces", said the Syrian Observatory for Human Rights, a Britain-based war monitor.

At the same time, Trump's declaration last week that he wants to pull U.S. troops out of northeastern Syria further undermines the impact that strikes might have on slowing the government's progress, said Faysal Itani of the Atlantic Council in Washington. A war-monitoring group said the airstrikes killed 14 people, including Iranians active in Syria.

Tehran, which usually remains mum about Israeli strikes harming its assets in Syria, acknowledged - through its semi-official media outlets - that Iranians were killed by Israel's warplanes, and vowed revenge.

The small USA force of about 2000 troops deployed in northeastern Syria alongside Syria's Kurds are particularly vulnerable to revenge attacks by both Iran and Syria, he said.

SANA news agency reported that the missile attack on the T4 military air base in Homs province resulted in a number of casualties, without giving details. It said the attack left people dead and wounded.

So far, the Israeli Defense Forces have also refused to either confirm or deny the statements made by the Russian Defense Ministry about the Israeli Air Force's involvement in the strikes, with IDF spokesman Jonathan Conricus telling Sputnik, "We do not comment on this". They have been denied proper education, food, healthcare, and have been forced to live in basements for months to shelter from attacks.

Eastern Ghouta, which is home to almost 400,000 people, fell to multiple militant groups in 2012, months after Syria plunged into crisis and has since served as a launch pad for fatal attacks against residents and infrastructure in Damascus.

In recent months, Israeli officials have been gravely concerned by Iran's efforts to build permanent military bases inside Syria.

Israel has repeatedly warned that it will not accept its arch-foe Iran entrenching itself militarily in Syria.