United scraped past Brighton & Hove Albion on Saturday to close the gap on City to five points, but Pep Guardiola's side stretched their advantage to eight points once again with a 2-1 win at Huddersfield Town on Sunday afternoon.
They are eighth in the league with 21 points under their belt, scoring 23 goals so far - more than the likes of Spurs and only 1 less than fourth-placed Arsenal.
"The work and attitude as a team. we don't change anything whether we play at home or away", he said.
United host their cross-city rivals on December 10 in a golden chance to close the gap.
United have been tight defensively this season, however, with just six goals conceded in 13 matches proving the best record in the division.
If seeing off Brighton at home was the hardest match of United's season how will Jose Mourinho's side fare at a ground where they were humbled 3-1 last season?
United are back in action on Wednesday night, with Mourinho's men travelling to Watford.
Watford are coming off an impressive 3-0 win against Newcastle What are the odds?
Richarlison has been on fire for Watford with five goals and three assistsWhat is the team news?
Marcos Rojo has started the last two matches after being sidelined by a knee issue of his own, although should Phil Jones or Eric Bailly return from injury the Argentina worldwide could be protected. Marcos Rojo is also in line to start as Mourinho considers selecting a three-man central defence.
Alongside the Frenchman, summer signing Nemanja Matic should assume his duties as the anchorman in the midfield for United.
Marouane Fellaini's involvement will depend on whether Mourinho selects two or three centre-backs for the clash in the capital.
An automatic choice between the sticks, the Spaniard will be looking to keep a second clean sheet in three days.